You prepare your drawing for plotting or publishing by specifying page setup settings. These settings are stored in the drawing file with the layout. Once a layout is established, you can modify the settings of its page setup or apply a different page setup.
Once you have completed a drawing, you can use a number of methods to output the drawing. You can plot the drawing on paper or create a file for use with another application. In either case, you select the plot settings.
You can easily publish an entire sheet set from the Sheet Set Manager as a set of paper drawings or as a single, electronic, multi-sheet DWF, DWFx, or PDF file.